The file or directory is corrupt and non-readable

SYMPTOMS:
:\ is not accessible
The file or directory is corrupt and non-readable.The file or directory is corrupt and non-readable. The file or directory \ is corrupt and unreadable.
Please Run the Chkdsk utility.

RESOLUTION: 
WARNING: When Chkdsk detects problems with the file system and attempts to repair the damage, data loss can occur. Microsoft does not recommend running Chkdsk with the /f command-line switch unless you have a full backup of your hard disk.

Attempt to repair the damaged file, folder or file system index using Chkdsk. To do so, follow these steps:

1. Click Start, and then click Run.
2. In the Open box, type chkdsk /f :, where is the letter of the drive on which the damaged file, folder or file system index exists.
3. Click OK.

NOTE: If the hard disk is large, Chkdsk may take several minutes to several hours to complete.